Gepubliceerde artikelen

Title / Author	Publication (Epub) date	Journal
A liquid biomarker signature of inflammatory proteins accurately predicts early pancreatic cancer progression during FOLFIRINOX chemotherapy. van Eijck CWF, Sabroso-Lasa S, Strijk GJ, Mustafa DAM, Fellah A, Koerkamp BG, Malats N, van Eijck CHJ.	31-01-2024	Neoplasia. 2024	Artikel lezen
FOLFIRINOX chemotherapy modulates the peripheral immune landscape in pancreatic cancer: Implications for combination therapies and early response prediction Casper W.F. van Eijck, Gaby Strijk, Eveline E. Vietsch, Fleur van der Sijde, Maaike Verheij, Dana A.M. Mustafa, Madelief Vink, Joachim G.J.V. Aerts, Casper H. J. van Eijcka, Marcella Willemsen	17-11-2023	European Journal of Cancer	Artikel lezen
B cell immune profiles in dysbiotic vermiform appendixes of pancreatic cancer patients Eveline E. Vietsch, Diba Latifi, Maaike Verheij, Elise W.A. van der Oost, Roeland F. de Wilde, Roel Haen, Anne Loes van den Boom, Bas Groot Koerkamp, Pascal G. Doornebosch, Victorien M.T. van Verschuer, Ariadne H.A.G. Ooms, Farzana Mohammad, Marcella Willemsen, Joachim G.J.V. Aerts, Ricki T. Krog, Noel F.C.C. de Miranda, Thierry P.P. van den Bosch, Yvonne M. Mueller, Peter D. Katsikis and Casper H.J. van Eijck	10-11-2023	Frontiers	Artikel lezen
Overexpression of the adhesion signaling pathway is linked to short- term survival in pancreatic ductal adenocarcinoma M.H. Aziz, L. Saida, C.H.J. van Eijck, D.A.M. Mustafa b	01-11-2023	Elsevier, Pancreatology	Artikel lezen
Analyzing Flow Cytometry or Targeted Gene Expression Data Influences Clinical Discoveries—Profiling Blood Samples of Pancreatic Ductal Adenocarcinoma Patients Willem de Koning, Casper W. F. van Eijck, Fleur van der Sijde, Gaby J. Strijk, Astrid A. M. Oostvogels, Reno Debets, Casper H. J. van Eijck, and Dana A. M. Mustafa	31-08-2023	Cancers	Artikel lezen
Enhanced antitumour immunity following neoadjuvant chemoradiotherapy mediates a favourable prognosis in women with resected pancreatic cancer Casper W F van Eijck, Dana A M Mustafa, Disha Vadgama, Noel F C C de Miranda, Bas Groot Koerkamp, Geertjan van Tienhoven, Sjoerd H van der Burg, Núria Malats Cancer Group (DPCG), Casper H J van Eijck, Dutch Pancreatic	01-08-2023	BMJ Journals	Artikel lezen
Rintatolimod: a potential treatment in patients with pancreatic cancer expressing Toll-like receptor 3 Hassana El Haddaoui, Casper WF van Eijck, Michail Doukas, Thierry PP van den Bosch, Peter M van Koetsveld, Leo J Hofland, Dana AM Mustafa, Casper HJ van Eijck.	15-06-2023	American Journal of Cancer Research	Artikel lezen
Immunostimulatory Profile of Cancer Cell Death by the AdV-Lumc007-Derived Oncolytic Virus ‘GoraVir’ in Cultured Pancreatic Cancer Cells Selas T. F. Bots, Sanne L. Landman, Martijn J. W. E. Rabelink, Diana J. M. van den Wollenberg and Rob C. Hoeben	19-01-2023	Viruses	Artikel lezen
Preclinical evaluation of the gorilla-derived HAdV-B AdV-lumc007 oncolytic adenovirus ‘GoraVir’ for the treatment of pancreatic ductal adenocarcinoma Selas T.F. Bots, Tom J. Harryvan, Christianne Groeneveldt, Priscilla Kinderman, Vera Kemp, Nadine van Montfoort, and Rob C. Hoeben	2023	Molecular Oncology	Artikel lezen
A multigene circulating biomarker to predict the lack of FOLFIRINOX response after a single cycle in patients with pancreatic ductal adenocarcinoma Casper W.F. van Eijck, Willem de Koning, Fleur van der Sijde, Miranda Moskie, Bas Groot Koerkamp, Marjolein Y.V. Homs, Sjoerd H. van der Burg, Casper H.J. van Eijck, Dana A.M. Mustafa	28-12-2022	Cancers	Artikel lezen
Genome Analyses of Ten New Ape Adenoviruses with Similarity to Human Mastadenovirus C Selas T. F. Bots, Vera Kemp, Iris J. C. Dautzenberg and Rob C. Hoeben	30-08-2022	International Journal of Molecular Science	Artikel lezen
Comparison between intratumoral and intravenously administered oncolytic virus therapy with Newcastle disease virus in a xenograft murine model for pancreatic adenocarcinoma J. Frederique de Graaf, Marco Huberts, Daphne Groeneveld, Stefan van Nieuwkoop, Casper H.J. van Eijck, Ron A.M. Fouchier, Bernadette G. van den Hoogen	05-07-2022	Heliyon	Artikel lezen
Optimizing environmental safety and cell- killing potential of oncolytic Newcastle Disease virus with modifications of the V, F and HN genes J. Frederique de Graaf, Stefan van Nieuwkoop, Theo Bestebroer, Daphne Groeneveld, Casper H. J. van Eijck, Ron A. M. Fouchier, Bernadette G. van den Hoogen	09-02-2022	Plos One	Artikel lezen
Robust deep learning model for prognostic stratification of pancreatic ductal adenocarcinoma patients. Jie Ju, Leonoor V. Wismans, Dana A.M. Mustafa, Marcel J.T. Reinders, Casper H.J. van Eijck, Andrew P. Stubbs & Yunlei Li.	17-12-2021	iScience	Artikel lezen
Non-human primate adenoviruses of the Human Adenovirus B species are potent and broadly-acting oncolytic vector candidates Ms. Selas TF Bots, Dr. Vera Kemp, Mr. Steve J Cramer, Dr. Diana JM van den Wollenberg, Dr. Marten Hornsveld, Dr. Martine Lamfers, Dr. Gabri van der Pluijm, and Prof. Rob C Hoeben	03-12-2021	Human Gene Therapy	Artikel lezen
Organoids derived from neoadjuvant FOLFIRINOX patients recapitulate therapy resistance in pancreatic ductal adenocarcinoma Elham Aida Farshadi, Jiang Chang, Brad Sampadi, Michail Doukas, Freek Van ‘t Land, Fleur van der Sijde, Eveline E. Vietsch, Joris Pothof, Bas Groot Koerkamp, Casper H.J. van Eijck.	27-09-2021	Clinical Cancer Research	Artikel lezen
The Multifaceted Role of Macrophages in Oncolytic Virotherapy. Hofman L, Lawler SE, Lamfers MLM.	13-08-2021	Viruses	Artikel lezen
The Role of the Respiratory Microbiome and Viral Presence in Lower Respiratory Tract Infection Severity in the First Five Years of Life Ivo Hoefnagels, Josephine van de Maat, Jeroen J.A. van Kampen, Annemarie van Rossum, Charlie Obihara, Gerdien A. Tramper-Stranders, Astrid P. Heikema, Willem de Koning, Anne-Marie van Wermerskerken, Deborah Horst-Kreft, Gertjan J.A. Driessen, Janine Punt, Frank J. Smit, Andrew Stubbs, Jeroen G. Noordzij, John P. Hays and Rianne Oostenbrink	05-07-2021	Micro organisms	Artikel lezen
Rintatolimod Induces Antiviral Activities in Human Pancreatic Cancer Cells: Opening for an Anti-COVID-19 Opportunity in Cancer Patients? Dana A. M. Mustafa, Lawlaw Saida, Diba Latifi, Leonoor V. Wismans, Willem de Koning, Lona Zeneyedpour, Theo M. Luider, Bernadette van den Hoogen and Casper H. J. van Eijck	09-06-2021	Cancers	Artikel lezen
Reovirus mutant jin-3 exhibits lytic and immune-stimulatory effects in preclinical human prostate cancer models. van de Merbel AF, van der Horst G, van der Mark MH, Bots STF, van den Wollenberg DJM, de Ridder CMA, Stuurman D, Aalders T, Erkens-Schulz S, van Montfoort N, Karthaus WR, Mehra N, Smits M, Schalken JA, van Weerden WM, Hoeben RC, van der Pluijm G	01-06-2021	Cancer Gene Ther. 2021 Jun 16	Artikel lezen
Identification, Validation, and Utilization of Immune Cells in Pancreatic Ductal Adenocarcinoma Based on Marker Genes Willem de Koning, Diba Latifi, Yunlei Li, Casper H. J. van Eijck, Andrew P. Stubbs and Dana A. M. Mustafa	27-04-2021	Fontiers in Immunology	Artikel lezen
Personalizing Oncolytic Virotherapy for Glioblastoma: In Search of Biomarkers for Response. Stavrakaki E, Dirven, CMF, Lamfers MLM	04-02-2021	Cancers (Basel)	Artikel lezen
Patient-derived tumour models for personalized therapeutics in urological cancers van de Merbel AF, van der Horst G, van der Pluijm G	01-01-2021	Nat Rev Urol. 2021 Jan;18(1):33-45.	Artikel lezen
Determinants of the efficacy of viro-immunotherapy: a review. de Graaf JF, Hubert M, Fouchier RAM, van den Hoogen BG	01-12-2020	Cytokine Growth Factor Rev. 2020 Dec;56:124-132	Artikel lezen
NanoGalaxy: Nanopore long-read sequencing data analysis in Galaxy Willem de Koning, Milad Miladi, Saskia Hiltemann, Astrid Heikema, John P Hays, Stephan Flemming, Marius van den Beek, Dana A Mustafa, Rolf Backofen, Björn Grüning, Andrew P Stubbs	17-10-2020	GigaScience	Artikel lezen
Comparison of Illumina versus Nanopore 16S rRNA Gene Sequencing of the Human Nasal Microbiota Astrid P. Heikema, Deborah Horst-Kreft, Stefan A. Boers, Rick Jansen, Saskia D. Hiltemann, Willem de Koning, Robert Kraaij, Maria A. J. de Ridder, Chantal B. van Houten, Louis J. Bont, Andrew P. Stubbs and John P. Hays	21-09-2020	Genes	Artikel lezen
Adenovirus Receptor Expression in Cancer and Its Multifaceted Role in Oncolytic Adenovirus Therapy Lobke C.M. Hensen, Rob C. Hoeben and Selas T.F. Bots	17-09-2020	International Journal of Molecular Science	Artikel lezen
Determinants of the efficacy of viro-immunotherapy: A review J.F. de Graaf, M. Huberts, R.A.M. Fouchier, B.G. van den Hoogen	06-09-2020	Elsevier	Artikel lezen
Dendritic cell vaccination and CD40-agonist combination therapy licenses T cell-dependent antitumor immunity in a pancreatic carcinoma murine model Lau, S.P.	20-07-2020	J Immunother Cancer	Artikel lezen
Non-Human Primate-Derived Adenoviruses for Future Use as Oncolytic Agents? Selas T.F. Bots and Rob C. Hoeben	08-07-2020	International Journal of Molecular Science	Artikel lezen
RNA from stabilized whole blood enables more comprehensive immune gene expression profiling compared to RNA from peripheral blood mononuclear cells Fleur van der Sijde, Yunlei Li, Rick Schraauwen, Willem de Koning, Casper H.J. van Eijck, Dana A. M. Mustafa	26-06-2020	PLoS ONE	Artikel lezen
Developing oncolytic viruses for clinical use: A consortium approach. Kemp V, Lamfers MLM, van der Pluijm G, van den Hoogen BG, Hoeben RC	10-06-2020	Cytokine Growth Factor Rev. 2020 Dec;56:133-140	Artikel lezen
Lessons learnt from the introduction of nanopore sequencing A. Heikema, W. de Koning, Y. Li, A. Stubbs, J.P. Hays	04-06-2020	Clinical Microbiology and Infection	Artikel lezen
Het Pancreascarcinoom: toch niet immuun voor therapie? Ontwikkelingen in de immuuntherapie voor ductal adenocarcinoom van het pancreas. Lau, S.P.	26-09-2019	Nederlands Tijdschrift voor Oncologie	Artikel lezen
Armed oncolytic viruses: A kick-start for anti-tumor immunity. de Graaf, JF, de Vor L, Fouchier RAM, van den Hoogen BG.	01-06-2018	Cytokine Growth Factor Rev. 2018; 41:28-39.	Artikel lezen
Rationally combining immunotherapies to improve efficacy of immune checkpoint blockade in solid tumors Dammeijer, F. & Lau, S.P.	28-06-2017	Cytokine Growth Factor Rev	Artikel lezen
Autologous Dendritic cells pulsed with allogeneic tumor cell lysate induce tumor-reactive T-cell responses in pancreatic cancer patients: immunological analysis of an ongoing phase II study Lau, S.P.	n/a	Clin Can Res (under revision)

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